The SISEM-SP works on five different main lines: Connection, Technical Support, Communication, Training and Promotion. These lines of action were structured aiming to qualify, improve and appreciate the organizations and museological collections from São Paulo. They are developed in partnership with other units of the Secretariat of Culture and Creative Economy of the State of São Paulo, the Social Organizations of Culture – responsible by the management of the Secretariat’s museum – and Prefectures.

An important initiative is the ProAC’s support – Cultural Action Program for releasing edicts turned to the museums field.